general transcription factors การใช้

• General transcription factors are necessary for transcription to occur.
• First, an RNA polymerase along with general transcription factors binds to the preinitiation complex.
• The encoded protein has been shown to interact with general transcription factor IIB, a basal transcription factor.
• CDK7 is both a CDK-activating kinase ( CAK ) and a component of the general transcription factor TFIIH.
• NcRNAs also target general transcription factors required for the Yik 2003 ), thereby repressing global elongation under stressful conditions.
• EBNA2 has an acidic activation domain, which can interact with many different general transcription factors and co-activators.
• In eukaryotes, an important class of transcription factors called general transcription factors ( GTFs ) are necessary for transcription to occur.
• RNA polymerase core enzyme binds to the bacterial general transcription factor sigma to form RNA polymerase holoenzyme and then binds to a promoter.
• The minimal PIC includes RNA polymerase II and six general transcription factors : TFIIA, chromatin remodeling complexes may also be components of the PIC.
• In classical silencers, the gene is actively repressed by the silencer element, mostly by interfering with general transcription factor ( GTF ) assembly.
• As a class of protein, general transcription factors bind to promoters along the DNA sequence or form a large transcription preinitiation complex to activate transcription.
• Mediator has been shown to associate with general transcription factors, as well as RNA polymerase II, and is essential for activator-dependent transcription.
• TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors to facilitate complex assembly and transcription initiation.
• Similar to the sigma factors in prokaryotes, the general transcription factors ( GTFs ) are a set of factors in eukaryotes that are required for all transcription events.
• TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors ( GTFs ) to facilitate complex assembly and transcription initiation.
• "' Transcription factor II E "'( TF II E ) is one of several general transcription factors that make up the RNA polymerase II preinitiation complex.
• This protein has also been found to act as a transcriptional coactivator by interconnecting the general transcription factor TATA element-binding protein ( TBP ) and gene-specific activators.
• As the CTD is frequently not required for general transcription factor ( GTF )-mediated initiation and RNA synthesis, it does not form a part of the catalytic essence of RNAPII, but performs other functions.
• Later in the 2000's, post-genomic research in his laboratory established signature proteins in halophilic Archaea, and the function of many genes and genetic elements, including multiple replication origins, general transcription factors, and DNA repair systems.
• TFIIB also directly interacts with TFIIF, another general transcription factor, however it is unclear how TFIIB and TFIIF work together in this mechanism as TFIIB is capable of binding RNA polymerase II both when it is bound to TFIIF and when it is not.